CD11b anticorps

N° du produit ABIN1820248

Cet anticorps Rat Monoclonal détecte spécifiquement CD11b dans FACS, IHC, IP, IF, IHC (fro) et Func. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour CD11b anticorps (ABIN1820248)

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivité: Humain, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD11b est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: 5C6

Détail du produit anti-CD11b anticorps

Specificité: Recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. The antibody immunoprecipitates a heterodimer of 165 and 95kD. Clone 5C6 exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.

Purification: Protein G purified

niveau d'endotoxine: Low Endotoxin

Immunogène: Thioglycollate-elicited Peritoneal Macrophages (TPM).

Isotype: IgG2b

Information d'application

Indications d'application: Approved: Flo (1:50 - 1:100), Func, IF, IHC, IHC-Fr, IP

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur CD11b

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Autre désignation: ITGAM / CD11b

Sujet: Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

ID gène: 3684

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation